Therapeutic efficacy of <sup>211</sup>At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer
نویسندگان
چکیده
We developed 211 At-radiolabeled 2,6-diisopropylphenyl azide (ADIPA) for targeted α-particle therapy. In the experiment using a mouse model, low-dose (70 kBq) administration of ADIPA effectively suppressed tumor growth without causing adverse effects.
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2023
ISSN: ['2041-6520', '2041-6539']
DOI: https://doi.org/10.1039/d3sc02513f